Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Heart Failure ClinicsAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Healthy weight and obesity prevention: JACC health promotion series.J Am Coll Cardiol. 2018; 72: 1506-1531
- Trends in obesity and severe obesity prevalence in US youth and adults by sex and age, 2007-2008 to 2015-2016.JAMA. 2018; 319: 1723-1725
- Physical activity, fitness, and obesity in heart failure with preserved ejection fraction.JACC Heart Fail. 2018; 6: 975-982
- Obesity and the risk of heart failure.N Engl J Med. 2002; 347: 305-313
- Update on obesity and obesity paradox in heart failure.Prog Cardiovasc Dis. 2016; 58: 393-400
- Obesity and the obesity paradox in heart failure.Prog Cardiovasc Dis. 2018; 61: 151-156
- Obesity and cardiac remodeling in adults: mechanisms and clinical implications.Prog Cardiovasc Dis. 2018; 61: 114-123
- Predictors of new-onset heart failure: differences in preserved versus reduced ejection fraction.Circ Heart Fail. 2013; 6: 279-286
- Relationship between physical activity, body mass index, and risk of heart failure.J Am Coll Cardiol. 2017; 69: 1129-1142
- Dose-response relationship between physical activity and risk of heart failure: a meta-analysis.Circulation. 2015; 132: 1786-1794
- Physical fitness and risk for heart failure and coronary artery disease.Circ Heart Fail. 2013; 6: 627-634
- Changes in mid-life fitness predicts heart failure risk at a later age independent of interval development of cardiac and noncardiac risk factors: the Cooper Center Longitudinal Study.Am Heart J. 2015; 169: 290-297.e1
- Obesity and heart failure: focus on the obesity paradox.Mayo Clin Proc. 2017; 92: 266-279
- The relationship between obesity and mortality in patients with heart failure.J Am Coll Cardiol. 2001; 38: 789-795
- Meta-analysis of the relation of body mass index to all-cause and cardiovascular mortality and hospitalization in patients with chronic heart failure.Am J Cardiol. 2015; 115: 1428-1434
- The obesity paradox in heart failure: is it all about fitness, fat, or sex?.JACC Heart Fail. 2015; 3: 927-930
- The heart failure overweight/obesity survival paradox: the missing sex link.JACC Heart Fail. 2015; 3: 917-926
- Body mass index and mortality in acutely decompensated heart failure across the world: a global obesity paradox.J Am Coll Cardiol. 2014; 63: 778-785
- Pre-morbid body mass index and mortality after incident heart failure: the ARIC Study.J Am Coll Cardiol. 2014; 64: 2743-2749
- Body composition and prognosis in chronic systolic heart failure: the obesity paradox.Am J Cardiol. 2003; 91: 891-894
- Waist circumference, body mass index, and survival in systolic heart failure: the obesity paradox revisited.J Card Fail. 2011; 17: 374-380
- The obesity paradox in men versus women with systolic heart failure.Am J Cardiol. 2012; 110: 77-82
- Adipose composition and heart failure prognosis: paradox or not?.J Am Coll Cardiol. 2017; 70: 2750-2751
- Abdominal obesity is associated with an increased risk of all-cause mortality in patients with HFpEF.J Am Coll Cardiol. 2017; 70: 2739-2749
- Impact of obesity and the obesity paradox on prevalence and prognosis in heart failure.JACC Heart Fail. 2013; 1: 93-102
- Importance of assessing cardiorespiratory fitness in clinical practice: a case for fitness as a clinical vital sign: a scientific statement from the American Heart Association.Circulation. 2016; 134: e653-e699
- Cardiorespiratory fitness, body mass index and heart failure incidence.Eur J Heart Fail. 2019; 21: 436-444
- Impact of cardiorespiratory fitness on the obesity paradox in patients with heart failure.Mayo Clin Proc. 2013; 88: 251-258
- Exercise capacity and the obesity paradox in heart failure: the FIT (Henry Ford Exercise Testing) Project.Mayo Clin Proc. 2018; 93: 701-708
- VO2max/kg is expected to be lower in obese individuals!.Int J Cardiol. 2015; 189: 234
- Is low VO2max/kg in obese heart failure patients indicative of cardiac dysfunction?.Int J Cardiol. 2015; 184: 755-762
- The incremental prognostic importance of body fat adjusted peak oxygen consumption in chronic heart failure.J Am Coll Cardiol. 2000; 36: 2126-2131
- Value of peak exercise oxygen consumption for optimal timing of cardiac transplantation in ambulatory patients with heart failure.Circulation. 1991; 83: 778-786
- How useful is body mass index for comparison of body fatness across age, sex, and ethnic groups?.Am J Epidemiol. 1996; 143: 228-239
- Obesity and diastolic heart failure: is inflammation the link?.Translational Medicine. 2013; 03: e124
- Pathophysiology of human visceral obesity: an update.Physiol Rev. 2013; 93: 359-404
- Leptin resistance and diet-induced obesity: central and peripheral actions of leptin.Metabolism. 2015; 64: 35-46
- Plasma leptin levels and incidence of heart failure, cardiovascular disease, and total mortality in elderly individuals.Diabetes Care. 2009; 32: 612-616
- Obesity contributes to exercise intolerance in heart failure with preserved ejection fraction.J Am Coll Cardiol. 2016; 68: 2487-2488
- Leptin and the ventilatory response to exercise in heart failure.J Am Coll Cardiol. 2003; 42: 1644-1649
- Leptin induces hypertension and endothelial dysfunction via aldosterone-dependent mechanisms in obese female mice.Hypertension. 2016; 67: 1020-1028
- The conundrum of patients with obesity, exercise intolerance, elevated ventricular filling pressures and a measured ejection fraction in the normal range.Eur J Heart Fail. 2019; 21: 156-162
- Resistin, adiponectin, and risk of heart failure the Framingham offspring study.J Am Coll Cardiol. 2009; 53: 754-762
- Role of resistin in cardiac contractility and hypertrophy.J Mol Cell Cardiol. 2008; 45: 270-280
- High leptin and resistin expression in chronic heart failure: adverse outcome in patients with dilated and inflammatory cardiomyopathy.Eur J Heart Fail. 2012; 14: 1265-1275
- Serum adiponectin level as an independent predictor of mortality in patients with congestive heart failure.Circ J. 2007; 71: 623-630
- Plasma adiponectin, body mass index, and mortality in patients with chronic heart failure.Circulation. 2005; 112: 1756-1762
- Circulating adiponectin concentrations in patients with congestive heart failure.Heart. 2006; 92: 1420-1424
- Adiponectin is released from the heart in patients with heart failure.Int J Cardiol. 2009; 132: 221-226
- Natriuretic peptides enhance the production of adiponectin in human adipocytes and in patients with chronic heart failure.J Am Coll Cardiol. 2009; 53: 2070-2077
- Regional adipose distribution and its relationship to exercise intolerance in older obese patients who have heart failure with preserved ejection fraction.JACC Heart Fail. 2018; 6: 640-649
- Impaired myocardial relaxation with exercise determines peak aerobic exercise capacity in heart failure with preserved ejection fraction.ESC Heart Fail. 2017; 4: 351-355
- Editorial commentary: obesity and heart failure with preserved ejection fraction: a single disease or two co-existing conditions?.Trends Cardiovasc Med. 2018; 28: 328-329
- Lean tissue imaging: a new era for nutritional assessment and intervention.JPEN J Parenter Enteral Nutr. 2014; 38: 940-953
- Comparison of sarcopenia and cachexia in men with chronic heart failure: results from the Studies Investigating Co-morbidities Aggravating Heart Failure (SICA-HF).Eur J Heart Fail. 2018; 20: 1580-1587
- Muscle wasting in patients with chronic heart failure: results from the studies investigating co-morbidities aggravating heart failure (SICA-HF).Eur Heart J. 2013; 34: 512-519
- Muscling up to improve heart failure prognosis.Eur J Heart Fail. 2018; 20: 1588-1590
- Lean mass abnormalities in heart failure: the role of sarcopenia, sarcopenic obesity and cachexia.Curr Probl Cardiol. 2019; ([Epub ahead of print])https://doi.org/10.1016/j.cpcardiol.2019.03.006
- Exercise intolerance in heart failure with preserved ejection fraction: diagnosing and ranking its causes using personalized O2 pathway analysis.Circulation. 2018; 137: 148-161
- Sedentary behavior, exercise and cardiovascular health.Circ Res. 2019; 124: 799-815
- Effect of aldosterone antagonism on exercise tolerance in heart failure with preserved ejection fraction.J Am Coll Cardiol. 2016; 68: 1823-1834
- A meta-analysis of the effect of exercise training on left ventricular remodeling in heart failure patients: the benefit depends on the type of training performed.J Am Coll Cardiol. 2007; 49: 2329-2336
- Exercise training in patients with severe left ventricular dysfunction. Hemodynamic and metabolic effects.Circulation. 1988; 78: 506-515
- Relation among body mass index, exercise training, and outcomes in chronic systolic heart failure.Am J Cardiol. 2011; 108: 1754-1759
- Efficacy and safety of exercise training in patients with chronic heart failure: HF-ACTION randomized controlled trial.JAMA. 2009; 301: 1439-1450
- Clinical outcomes and cardiovascular responses to different exercise training intensities in patients with heart failure: a systematic review and meta-analysis.JACC Heart Fail. 2013; 1: 514-522
- Relation between volume of exercise and clinical outcomes in patients with heart failure.J Am Coll Cardiol. 2012; 60: 1899-1905
- Exercise training in patients with heart failure and preserved ejection fraction: meta-analysis of randomized control trials.Circ Heart Fail. 2015; 8: 33-40
- Effect of caloric restriction or aerobic exercise training on peak oxygen consumption and quality of life in obese older patients with heart failure with preserved ejection fraction: a randomized clinical trial.JAMA. 2016; 315: 36-46
- Determinants of exercise intolerance in elderly heart failure patients with preserved ejection fraction.J Am Coll Cardiol. 2011; 58: 265-274
- Weight loss in obese patients with heart failure.J Am Heart Assoc. 2016; 5: e002468
- Relation of duration of morbid obesity to left ventricular mass, systolic function, and diastolic filling, and effect of weight loss.Am J Cardiol. 1995; 76: 1194-1197
- Cardiac morphology and left ventricular function in normotensive morbidly obese patients with and without congestive heart failure, and effect of weight loss.Am J Cardiol. 1997; 80: 736-740
- Long-Term effects of randomization to a weight loss intervention in older adults: a pilot study.J Nutr Gerontol Geriatr. 2019; 38: 83-99
- The danger of weight loss in the elderly.J Nutr Health Aging. 2008; 12: 487-491
- Dietary fat, sugar consumption, and cardiorespiratory fitness in patients with heart failure with preserved ejection fraction.JACC Basic Transl Sci. 2017; 2: 513-525
- Unsaturated Fatty Acids to Improve Cardiorespiratory Fitness in Patients With Obesity and HFpEF: The UFA-Preserved Pilot Study.JACC Basic Transl Sci. 2019 Aug 26; 4: 563-565https://doi.org/10.1016/j.jacbts.2019.04.001
Article info
Footnotes
Funding Support: S. Carbone is supported by a Career Development Award 19CDA34660318 from the American Heart Association.
Disclosures: The authors have nothing to disclose.
Identification
Copyright
© 2019 Elsevier Inc. All rights reserved.
