Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Heart Failure ClinicsAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- [2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension].Kardiol Pol. 2015; 73: 1127-1206
- Definitions and diagnosis of pulmonary hypertension.J Am Coll Cardiol. 2013; 62: D42-D50
- Haemodynamic definitions and updated clinical classification of pulmonary hypertension.Eur Respir J. 2019; 53https://doi.org/10.1183/13993003.01913-2018
- Updated treatment algorithm of pulmonary arterial hypertension.J Am Coll Cardiol. 2013; 62: D60-D72
- Gender-related differences in pulmonary arterial hypertension targeted drugs administration.Pharmacol Res. 2016; 114: 103-109
- Sex differences in pulmonary arterial hypertension: role of infection and autoimmunity in the pathogenesis of disease.Biol Sex Differ. 2018; 9: 15
- Molecular pathogenesis of pulmonary arterial hypertension.J Clin Invest Dec. 2012; 122: 4306-4313
- Progress in solving the sex hormone paradox in pulmonary hypertension.Am J Physiol Lung Cell Mol Physiol. 2014; 307: L7-L26
- Right Heart Failure in Pulmonary Hypertension.Cardiol Clin May. 2020; 38: 243-255
- The right ventricle under pressure: cellular and molecular mechanisms of right-heart failure in pulmonary hypertension.Chest Mar. 2009; 135: 794-804
- Causes and circumstances of death in pulmonary arterial hypertension.Am J Respir Crit Care Med. 2013; 188: 365-369
- Sex, Gender, and Sex Hormones in Pulmonary Hypertension and Right Ventricular Failure.Compr Physiol. 2019; 10: 125-170
- Pulmonary Hypertension in Women.Heart Fail Clin Jan. 2019; 15: 137-145
- SANRA-a scale for the quality assessment of narrative review articles.Res Integr Peer Rev. 2019; 4: 5
- Demystifying how to incorporate Sex and Gender into cardiovascular research: a practical guide.Can J Cardiol. 2022; https://doi.org/10.1016/j.cjca.2022.05.017
- REVEAL: a contemporary US pulmonary arterial hypertension registry.Eur Respir Rev Mar 01. 2012; 21: 8-18
- Survival in pulmonary hypertension in Spain: insights from the Spanish registry.Eur Respir J Sep. 2012; 40: 596-603
- Estrogen exposure, obesity and thyroid disease in women with severe pulmonary hypertension.Eur J Med Res Sep 28. 2009; 14: 433-442
- Alterations in oestrogen metabolism: implications for higher penetrance of familial pulmonary arterial hypertension in females.Eur Respir J Nov. 2009; 34: 1093-1099
- Sex hormones are associated with right ventricular structure and function: The MESA-right ventricle study.Am J Respir Crit Care Med Mar 01. 2011; 183: 659-667
- Sex and haemodynamics in pulmonary arterial hypertension.Eur Respir J Feb. 2014; 43: 523-530
- Pulmonary Arterial Hypertension in Women.Methodist Debakey Cardiovasc J. 2017; 13: 224-237
- Pulmonary vasodilatory action of testosterone: evidence of a calcium antagonistic action.J Cardiovasc Pharmacol Jun. 2002; 39: 814-823
- Selective estrogen receptor-alpha and estrogen receptor-beta agonists rapidly decrease pulmonary artery vasoconstriction by a nitric oxide-dependent mechanism.Am J Physiol Regul Integr Comp Physiol Nov. 2008; 295: R1486-R1493
- Endogenous estrogen attenuates pulmonary artery vasoreactivity and acute hypoxic pulmonary vasoconstriction: the effects of sex and menstrual cycle.Am J Physiol Endocrinol Metab Sep. 2007; 293: E865-E871
- Sex Differences, Estrogen Metabolism and Signaling in the Development of Pulmonary Arterial Hypertension.Front Cardiovasc Med. 2021; 8: 719058
- Higher Estradiol and Lower Dehydroepiandrosterone-Sulfate Levels Are Associated with Pulmonary Arterial Hypertension in Men.Am J Respir Crit Care Med. 2016; 193: 1168-1175
- Lower DHEA-S levels predict disease and worse outcomes in post-menopausal women with idiopathic, connective tissue disease- and congenital heart disease-associated pulmonary arterial hypertension.Eur Respir J. 2018; 51https://doi.org/10.1183/13993003.00467-2018
- Sex-dependent influence of endogenous estrogen in pulmonary hypertension.Am J Respir Crit Care Med. 2014; 190: 456-467
- Activity of the estrogen-metabolizing enzyme cytochrome P450 1B1 influences the development of pulmonary arterial hypertension.Circulation. 2012; 126: 1087-1098
- Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene.Am J Hum Genet Sep. 2000; 67: 737-744
- Genetics and genomics of pulmonary arterial hypertension.J Am Coll Cardiol. 2013; 62: D13-D21
- Genetics and genomics of pulmonary arterial hypertension.Eur Respir J. 2019; 53https://doi.org/10.1183/13993003.01899-2018
- EIF2AK4 Mutations in Patients Diagnosed With Pulmonary Arterial Hypertension.Chest. 04. 2017; 151: 821-828
- BMPR2 mutations and survival in pulmonary arterial hypertension: an individual participant data meta-analysis.Lancet Respir Med Feb. 2016; 4: 129-137
- Interleukin-6 (IL-6) rs1800796 and cyclin dependent kinase inhibitor (CDKN2A/CDKN2B) rs2383207 are associated with ischemic stroke in indigenous West African Men.J Neurol Sci. 2017; 379: 229-235
- Sex Differences in Inflammatory Responses to Adipose Tissue Lipolysis in Diet-Induced Obesity.Endocrinology. 2019; 160: 293-312
- Tubular carcinoma of the male breast: report of a case.Cancer Aug. 1975; 36: 462-465
- Sex-specific differences in peripheral blood leukocyte transcriptional response to LPS are enriched for HLA region and X chromosome genes.Sci Rep. 2021; 11: 1107
- COVID-19 and Individual Genetic Susceptibility/Receptivity: Role of ACE1/ACE2 Genes, Immunity, Inflammation and Coagulation. Might the Double X-chromosome in Females Be Protective against SARS-CoV-2 Compared to the Single X-Chromosome in Males?.Int J Mol Sci. 2020; 21https://doi.org/10.3390/ijms21103474
- The right ventricle explains sex differences in survival in idiopathic pulmonary arterial hypertension.Chest Jun. 2014; 145: 1230-1236
- Survival in patients with primary pulmonary hypertension. Results from a national prospective registry.Ann Intern Med. 1991; 115: 343-349
- Right ventricular adaptation and failure in pulmonary arterial hypertension.Can J Cardiol Apr. 2015; 31: 391-406
- Imaging the heart in pulmonary hypertension: an update.Eur Respir Rev Dec. 2015; 24: 653-664
- Sex matters in pulmonary arterial hypertension.Eur Respir J Aug. 2014; 44: 553-554
- The endothelin system in pulmonary arterial hypertension.Cardiovasc Res Feb. 2004; 61: 227-237
- Mechanisms of disease: pulmonary arterial hypertension.Nat Rev Cardiol. 2011; 8: 443-455
- Age- and sex-related variation of plasma endothelin-1 concentration in normal and hypertensive subjects.Am Heart J Apr. 1992; 123: 1092-1093
- Influence of sex hormones on plasma endothelin levels.Ann Intern Med Mar 15. 1993; 118: 429-432
- Sex differences in endothelin-1-mediated vasoconstrictor tone in middle-aged and older adults.Am J Physiol Regul Integr Comp Physiol Feb. 2010; 298: R261-R265
- 2015 ESC/ERS Guidelines for the Diagnosis and Treatment of Pulmonary Hypertension.Rev Esp Cardiol. 2016; 69: 177
- Clinical pharmacology of bosentan, a dual endothelin receptor antagonist.Clin Pharmacokinet. 2004; 43: 1089-1115
- Sildenafil citrate therapy for pulmonary arterial hypertension.N Engl J Med. 2005; 353: 2148-2157
- Distinct endothelial pathways underlie sexual dimorphism in vascular auto-regulation.Br J Pharmacol. Oct 2012; 167: 805-817
- Sex differences in response to tadalafil in pulmonary arterial hypertension.Chest. 2015; 147: 188-197
- Pulmonary arterial hypertension: from the kingdom of the near-dead to multiple clinical trial meta-analyses.Eur Heart J. 2010; 31: 2080-2086
- Evidence for a difference in nitric oxide biosynthesis between healthy women and men.Hypertension. 1998; 32: 730-734
- Change of right heart size and function by long-term therapy with riociguat in patients with pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension.Int J Cardiol. 2015; 195: 19-26
- Risk stratification and medical therapy of pulmonary arterial hypertension.Eur Respir J. 2019; 53https://doi.org/10.1183/13993003.01889-2018
- Effects of age and sex on the pharmacokinetics of the soluble guanylate cyclase stimulator riociguat (BAY 63-2521).Pulm Circ. 2016; 6: S58-S65
- A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension.N Engl J Med. 1996; 334: 296-301
- Treatment of primary pulmonary hypertension with continuous intravenous prostacyclin (epoprostenol). Results of a randomized trial.Ann Intern Med. 1990; 112: 485-491
- Pathways in pulmonary arterial hypertension: the future is here.Eur Respir Rev. 2012; 21: 321-327
- Sotatercept for the Treatment of Pulmonary Arterial Hypertension.N Engl J Med. 2021; 384: 1204-1215
- Sex and gender: modifiers of health, disease, and medicine.Lancet. 2020; 396: 565-582
- Better science with sex and gender: Facilitating the use of a sex and gender-based analysis in health research.Int J Equity Health. 2009; 8: 14
- Care of the Transgender Patient with a Pulmonary Complaint.Ann Am Thorac Soc. 2021; 18: 931-937
- Prevalence, Risk Factors and Intervention for Depression and Anxiety in Pulmonary Hypertension: A Systematic Review and Meta-analysis.Front Med (Lausanne). 2022; 9: 765461
- Anxiety and depression in patients with pulmonary hypertension.Psychosom Med. 2004; 66: 831-836
- Anxiety and depression disorders in patients with pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension.Respir Res. 2013; 14: 104
- The trajectory to diagnosis with pulmonary arterial hypertension: a qualitative study.BMJ Open. 2012; 2: e000806
- Living with pulmonary hypertension: unique insights from an international ethnographic study.BMJ Open. 2014; 4: e004735
- Quality of life and psychological symptoms in patients with pulmonary hypertension.Heart Lung. 2018; 47: 115-121
- Understanding the impact of pulmonary arterial hypertension on patients' and carers' lives.Eur Respir Rev. 2013; 22: 535-542
- Impact of Pulmonary Arterial Hypertension on Employment, Work Productivity, and Quality of Life - Results of a Cross-Sectional Multi-Center Study.Front Psychiatry. 2021; 12: 781532
- Health-related quality of life in patients with pulmonary arterial hypertension.Respir Res. 2005; 6: 92
- The importance of patient perspectives in pulmonary hypertension.Eur Respir J. 2019; 53https://doi.org/10.1183/13993003.01919-2018
- Health-related quality of life and psychological states in patients with pulmonary arterial hypertension.J Cardiovasc Nurs. 2014; 29: 178-184
- [Female gender and pulmonary arterial hypertension: a complex relationship].G Ital Cardiol (Rome). 2012; 13: 448-460
- Predictors of Maternal Death Among Women With Pulmonary Hypertension in China From 2012 to 2020: A Retrospective Single-Center Study.Front Cardiovasc Med. 2022; 9: 814557
- Occupational exposure to organic solvents: a risk factor for pulmonary veno-occlusive disease.Eur Respir J. 2015; 46: 1721-1731
- Pertussis vaccine: court finds no justification for association with permanent brain damage.Lancet. 1988; 1: 837
- Mediating effect of social support on the relationship between illness concealment and depression symptoms in patients with pulmonary arterial hypertension.Heart Lung. 2021; 50: 706-713
- Health Disparities in Patients with Pulmonary Arterial Hypertension: A Blueprint for Action. An Official American Thoracic Society Statement.Am J Respir Crit Care Med. 2017; 196: e32-e47
- Socioeconomic status affects pulmonary hypertension disease severity at time of first evaluation.Pulm Circ. 2016; 6: 191-195
- Lower socioeconomic status is associated with worse outcomes in pulmonary arterial hypertension.Am J Respir Crit Care Med. 2013; 187: 303-310
- Social deprivation in Scottish populations with pulmonary hypertension secondary to connective tissue disease and chronic thromboembolic disease.ERJ Open Res Oct. 2020; 6https://doi.org/10.1183/23120541.00297-2019
- Socioeconomic status and survival in patients with pulmonary hypertension.ERJ Open Res. 2020; 6https://doi.org/10.1183/23120541.00638-2020
- The Association Between Median Income and Severity of Pulmonary Hypertension at Diagnosis and Risk at Follow Up in a Public Health Care System.Am J Respir Crit Care Med. 2022; (Available at:)https://doi.org/10.1164/ajrccm-conference.2022.205.1_MeetingAbstracts.A5085
- Health Literacy and Health Outcomes in Chronic Obstructive Pulmonary Disease Patients: An Explorative Study.Front Public Health. 2022; 10: 846768
- Impact of patient characteristics and perceived barriers on referral to exercise rehabilitation among patients with pulmonary hypertension in the United States.Pulm Circ. 2020; 10 (2045894020974926)
- Readmission and death after an acute heart failure event: predictors and outcomes in sub-Saharan Africa: results from the THESUS-HF registry.Eur Heart J. 2013; 34: 3151-3159
- Wood smoke-associated lung disease: a clinical, functional, radiological and pathological description.Int J Tuberc Lung Dis. 2008; 12: 1092-1098
- Pulmonary arterial hypertension and cor pulmonale associated with chronic domestic woodsmoke inhalation.Chest. 1993; 103: 12-20
- Survival in pulmonary arterial hypertension: a reappraisal of the NIH risk stratification equation.Eur Respir J. 2010; 35: 1079-1087
- An epidemiological study of pulmonary arterial hypertension.Eur Respir J. 2007; 30: 104-109
- New predictors of outcome in idiopathic pulmonary arterial hypertension.Am J Cardiol. 2005; 95: 199-203
- Survival in incident and prevalent cohorts of patients with pulmonary arterial hypertension.Eur Respir J. 2010; 36: 549-555
- Pulmonary arterial hypertension in France: results from a national registry.Am J Respir Crit Care Med. 2006; 173: 1023-1030
- Survival in patients with idiopathic, familial, and anorexigen-associated pulmonary arterial hypertension in the modern management era.Circulation. 2010; 122: 156-163
- Changing demographics, epidemiology, and survival of incident pulmonary arterial hypertension: results from the pulmonary hypertension registry of the United Kingdom and Ireland.Am J Respir Crit Care Med. 2012; 186: 790-796
- Anticoagulation and survival in pulmonary arterial hypertension: results from the Comparative, Prospective Registry of Newly Initiated Therapies for Pulmonary Hypertension (COMPERA).Circulation. 2014; 129: 57-65
- Macitentan and morbidity and mortality in pulmonary arterial hypertension.N Engl J Med. 2013; 369: 809-818
- Relationship Between Time From Diagnosis and Morbidity/Mortality in Pulmonary Arterial Hypertension: Results From the Phase III GRIPHON Study.Chest. 2021; 160: 277-286
Article info
Identification
Copyright
© 2022 Elsevier Inc. All rights reserved.
